Table 1.
Treatment (µmol/L) |
Cell cycle distribution (%) |
Apoptosis (%) |
||
---|---|---|---|---|
G1/G0 | S | G2/M | ||
NT | 77.5 ± 0.3a | 14.7 ± 0.1a | 7.8 ± 0.4a | 3.5 ± 0.1a |
EGCG 40 | 74.6 ± 0.1b | 15.7 ± 0.3b | 9.7 ± 0.4b | 5.0 ± 0.3b |
Quer 10 | 72.3 ± 0.3c | 15.9 ± 0.2b | 11.8 ± 0.3c | 4.4 ± 0.1c |
Quer 20 | 67.6 ± 0.4d | 17.3 ± 0.4c | 15.1 ± 0.4d | 5.3 ± 0.1b |
EGCG 40 + Quer 10 | 60.6 ± 0.2e | 19.3 ± 0.2d | 20.1 ± 0.2e | 7.9 ± 0.3d |
EGCG 40 + Quer 20 | 50.0 ± 0.9f | 23.4 ± 0.2e | 26.6 ± 0.9f | 9.5 ± 0.3e |
PC-3 cells were treated with the indicated concentrations of EGCG and quercetin alone or in combination. Cell cycle distribution and cell apoptosis were detected at 48h post treatment by flow cytometry. Data are presented as mean ± SD. Groups with different superscript letters in each column represent significant difference between groups (P<0.05).