Table 1.

Summary of the clinical descriptions of the affected individuals

Patients	II-1	II-5	II-8	II-9
Gender	Female	Female	Male	Female
Age at onset	13	14	13	16
Age at examination	35	31	26	28
Rigidity	+++	+++	+	+
Akinesia	+++	++	+++	++
Rest tremor	++	–	–	N/A
Dysarthria/dysphasia	++	+	++	+
Uncoordinated movements	+	–	+	+
Behavioural instability	++	–	+	–
Intellectual impairment	++	+	+	+
Response to levodopa	+++	+++	++	+

Adapted from (8).