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ERK5 icKO mice are deficient in pattern separation. A, Schematic illustration of the experimental design. B, ERK5 icKO mice made fewer correct choices in both the easier (separation 4) and more difficult (separation 2) pattern separations. Data are from the last day of a 5 d experimental paradigm and represent mean ± SEM with n ≥ 10 per treatment group. *p < 0.05.
