Figure 7.

Schematic view of the medial temporal lobe memory system. The entorhinal cortex is a major source of projections to the hippocampal region (which includes the dentate gyrus, the cell fields of the hippocampus, and the subicular complex). Nearly two-thirds of the cortical input to entorhinal cortex originates in the adjacent perirhinal and parahippocampal cortices, which in turn receive projections from unimodal and polymodal areas in the frontal, temporal, and parietal lobes. The entorhinal cortex also receives other direct inputs from orbital frontal cortex, insular cortex, and superior temporal gyrus. All these projections are reciprocal.