The acute toxicity of the nanomaterials in vivo. The newborn chicks (n = 10 per group) were fed once with 500 mg/kg nanoscale silicate platelet (NSP), 500 mg/kg silver nanoparticle (AgNP)/NSP, or 187.5 mg/kg AgNPs at postnatal 12 hours. The silver nanomaterials were given at the same silver content. (A) The surviving animals were recorded, and the chicks were weighed every day until day 7. (B) The weight data on day 7 are shown. (C and D) The organs of 1-week-old chicks (n = 3) were collected and oven-dried, and their silver deposits were determined by inductively coupled plasma-mass spectrometry.
Notes: The values indicate the silver concentrations in the wet tissues. The data represent two independent experiments. *P < 0.05 (one-way analysis of variance).