Figure 4.

VGF intrahippocampal infusions decrease immobility in FST. A, Mice were injected bilaterally with saline, VGF (100 ng), or BDNF (500 ng) and scored on FST (6 min) performed 3 and 6 d postsurgery. The bars represent average time spent immobile for all animals ± SE (n = 5). *p < 0.05, t test. B, Mice were also scored for locomotor behavior in the open field test. The bars represent the average number of quadrant crossings ± SE in a 15 min time period scored 3 and 6 d after surgery (n = 5). *p < 0.05, t test.