Fig. 2.

Algorithm for POC coagulation management in trauma surgery at the Department of Anaesthesiology and Intensive Care Medicine, University Hospital Essen, Germany. Thromboelastometric variables and assays: CT = clotting time; A10 = amplitude of clot firmness after 10 min; ML = maximum lysis. Assays: EX = ExTEM^®; FIB = FibTEM^®; IN = InTEM^®; HEP = HepTEM^®. Other abbreviations: Tc = core temperature; Cai = ionised calcium; Hb = haemoglobin; ISS = injury severity score; PT = prothrombin time; bw = body weight; PCC = prothrombin complex concentrate; FFP = fresh frozen plasma; DDAVP = desmopressin; F VIII/vWF concentrate = factor VIII/von Willebrand factor concentrate; F XIII = factor XIII concentrate; rFVIIa = activated recombinant factor VII.