Table 2. Correlations between miRNA-143 expression and clinico-pathological parameters.
miRNA-143 expression
|
|||
---|---|---|---|
Clinico-pathological parameter | miRNA-143 low ( n =41) | miRNA-143 high ( n =36) | P -value |
Age (years) | |||
<60 | 17 (40.4%) | 18 (50%) | 0.453 |
⩾60 | 24 (59.6%) | 18 (50%) | |
Gender | |||
Male | 30 (73.2%) | 22 (61.1%) | 0.259 |
Female | 11 (26.8%) | 14 (38.9%) | |
Tumour location | |||
Colon | 25 (61%) | 24 (66.7%) | 0.604 |
Rectum | 16 (39%) | 12 (33.3%) | |
Tumour grade | |||
G1 | 1 (2.4%) | 1 (2.8%) | 0.495 |
G2 | 28 (68.3%) | 27 (75%) | |
G3 | 12 (29.3%) | 8 (22.2%) | |
Stage | |||
II–III | 14 (34.1%) | 18 (50%) | 0.137 |
IV | 27 (65.9%) | 18 (50%) | |
Levels of tumour marker (median ng ml−1) | |||
CEA | 4 | 3 | 0.606 |
Abbreviations: CEA=carcinoembryonic antigen; miRNA=microRNA.