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. Author manuscript; available in PMC: 2013 May 24.
Published in final edited form as: J Med Chem. 2012 May 16;55(10):4640–4651. doi: 10.1021/jm300460c

Figure 3.

Figure 3

Identification of 31b’s reaction partner. ● Alexa Fluor-labeled SRC2-3 peptide (7 nM) was incubated for 3 hours with different concentration of 31b followed by the addition of VDR-LBD (1 μM) and LG190178 (5 μM). Fluorescence polarization was detected after 5 minutes. ■ VDR-LBD (1 μM) and LG190178 (5 μM) was incubated for 3 hours with different concentration of 31b followed by the addition of Alexa Fluor-labeled SRC2-3 peptide (7 nM). Fluorescence polarization was detected after 5 minutes.