Table 1. Cytogenetic and array analysis of HC-AFW1 cells.
| Hepatoblastoma* | Hepatocellular carcinoma* | Cytogenetic analysis and FISH of HC-AFW1 | Array of HC-AFW1 |
| Gain of 1 | Loss of 1p (33%)Loss of 1q (22%) | Gain of complete 1q and loss of complete 1p by isochromosome 1q formationInterstitial deletion of 1q32–43 | Gain of complete 1qLoss of complete 1p |
| Gain of 2qFrequent breaks in 2q35-q37 | Gain of subtelomeric 2p: terminal 2p at 3pgain of subtelomeric 2q: der(4)t(2;4)(q36?;q31) | Gain of 2p25.3 (15 Mb)Gain of 2q24.1-qter | |
| Derivative chromosome 3 with terminal 2p at 3p and gain of unclear chromosomal material in 3q | Gain of 3pter-p24.3 (20 Mb) Gain of 3q29 | ||
| Loss of 4q | Loss of 4q (38%) | deletion of 4q31-qterder(4)t(4;2)(q31;q36?) | Loss of 4q21.22-qter |
| Interstitial deletion of 5q15–35.2Gain of terminal 5q (signal at a D-chromosome) | |||
| Loss of 6q (29%) [IGF2R] | No IGF2R deletion | ||
| Gain of 7 | |||
| Gain of 8 | Loss of 8p (48%) | ||
| Loss of 9p (20%) [p16] | Gain of 9q33.1-qterNo p16 deletion | ||
| Derivative chromosome 11 with unclear additional material in p and q | Loss of 11pter-p14.1Gain of 11p13.3-q12.2Loss of 11q13.4-qter | ||
| Loss of 13q (31%) [RB1] | No RB1 deletion | ||
| Loss of 16q (30%)Loss of 16p (24%) [Axin 1] | No Axin1 deletion | ||
| Gain of 17 | Loss of 17p (45%) [p53] | No p53 deletion | |
| Gain of 19pter-p13.11 | |||
| Gain of 20 | Gain of complete 20 | ||
| Monosomy 21 | |||
| Gain of 22q | Duplication of 22q11.2–13 | Gain of 22q12.1 | |
| t(1;4)(q12;q34) resulting in partial trisomy 1q and partial monosomy 4q | Additional marker chromosome, maybe a complex derivative of 19 with 20q at the short arm |
*
According to the Atlas of Genetics and Cytogenetics in Oncology and Haematology.