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TEM micrographs of double-labeling of pKu70 (10-nm beads) and p53BP1 (6-nm beads) at different magnifications. In enterocytes of small intestine, keratinocytes of skin as well as in human fibroblast, radiation-induced pKu70 clusters (consisting of 2 gold beads, red arrows) co-localize with 53BP1 only in heterochromatic regions.
