Figure 6. Invasion assays of A549 and H1299 cells transfected with control and TRIM24-specific siRNA.

TRIM24 siRNA treatment have a measurable blocking effect on cell invasion in both cell lines. Numbers of cells invading onto the lower surface of the filter were counted, a significant difference was observed (A, p<0.05). Columns, mean; bars, SD. There was no significant change of MMP2 and MMP9 expression levels after TRIM24 knockdown (B). *p<0.05.