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. 2012 May 30;7(5):e37608. doi: 10.1371/journal.pone.0037608

Table 4. Predicted top 20 scoring target proteins of MDMA.

Protein name UniProt ID Binding score
Beta-1 adrenergic receptor P08588 0.820
Carbonic anhydrase 2 P00918 0.810
Prothrombin P00734 0.804
Alpha-2A adrenergic receptor P08913 0.802
Prostaglandin G/H synthase 2 P35354 0.800
Dipeptidyl peptidase 4 P27284 0.798
Acetylcholinesterase P22303 0.796
Nitric-oxide synthase, endothelial P29474 0.794
Beta-2 adrenergic receptor P07550 0.794
Prostaglandin G/H synthase 1 P23219 0.784
Gag-Pol polyprotein P12497 0.778
Nitric oxide synthase, inducible P35228 0.770
Glutamate receptor 2 P42262 0.770
Alpha-2C adrenergic receptor P18825 0.768
5-hydroxytryptamine 2A receptor P28223 0.766
Alpha-1A adrenergic receptor P35348 0.764
cAMP-dependent protein kinase catalytic subunit alpha P17612 0.760
Gag-Pol polyprotein P03366 0.758
Gamma-aminobutyric-acid receptor subunit alpha-1 P14867 0.754
Gag-Pol polyprotein P03367 0.752