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. 2012 Apr 14;13(2):582–589. doi: 10.1208/s12249-012-9777-4

Table III.

Log Reduction of Biological Indicators by Peroxyacetic Acid

Log reduction (n = 1)
1 μL PAA (0.32 mg/mL) 5 μL PAA (1.6 mg/mL) 5 μL PAA (1.6 mg/mL) no LP
G. stearothermophilus 7.52 7.52 7.52
B. atrophaeus 7.74 7.74 7.74
B. pumilus 3.61 6.30 6.54

One or five microliters of 32 % peroxyacetic acid were placed directly into 1 mL of a solution of 60 mg/mL acetaminophen in ethanol and ~2 × 107 CFU of biological indicators. Two sets of vials were then subjected to lyophobic precipitation at 37 °C, 1,175 psi scCO2 with sonication for 55 min while the third set was allowed to incubate at room temperature for the duration of the experiment