Table V.

Stability Analysis of Acetaminophen Exposed to PAA and Dried by Lyophobic Precipitation

		HPLC analysis of acetaminophen
Peak identity	R.R.T.	Standard	Sample 1	Sample 2	Test (n = 2)
		n = 2	Acetaminophen plus 320 μg PAA, no LP	Acetaminophen plus 1.6 mg PAA, no LP	Acetaminophen plus 160 μg PAA, LP
		Total %	Total %	Total %	Total %
	1.7	0.18	0.02	0.15	0.12
	1.9	0.10	0.36	11.28	0.14
	2.4	0.03	0.64	18.54	0.03
	2.7
	2.9		0.01	0.69
Acetaminophen	3.9	100	100	100	100
	4.4		0.11	4.23
	5.8			0.06
	6.5	0.05	0.01	0.10	0.02
	7.3	0.07		0.04	0.07
Total percent degradation products		0.43	1.15	35.10	0.37

Sample 1 is acetaminophen exposed to 320 μg PAA for 30 min prior to HPLC analysis; Sample 2 is acetaminophen exposed to 1.6 mg PAA for 30 min prior to HPLC analysis; Test is average of two samples of acetaminophen exposed to 160 μg PAA then dried by lyophobic precipitation prior to HPLC analysis; RRT relative retention time (relative to acetaminophen peak)