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. 2011 Sep;80(3):486–497. doi: 10.1124/mol.111.072884

Fig. 3.

Fig. 3.

Characterization of cAMP accumulation in the presence of GLP-1(1–36)NH2 (A), GLP-1(7–36)NH2 (B), exendin-4 (C), oxyntomodulin (D), and compound 2 (E) in FlpInCHO cells stably expressing each of the human GLP-1R polymorphisms or the wild-type GLP-1R. Data are normalized to the response elicited by 100 nM forskolin and analyzed with a three-parameter logistic equation as defined in eq. 1. All values are mean ± S.E.M. of 4 to 12 experiments conducted in duplicate.