Table 2.
Average number of H bonds between T-1249 aminoacid residues (or some relevant aminoacid residues) and relevant atoms in the bilayer structure.
| Phosphate O atoms | O16 (carbonyl O atom of sn-2 chain) | OH Chol | |||
|---|---|---|---|---|---|
| POPC | POPC : Chol | POPC | POPC : Chol | POPC : Chol | |
| T-1249 | 9.62 ± 0.63 | 5.60 ± 1.09 | 1.63 ± 0.22 | 0.75 ± 0.13 | 0.86 ± 0.10 |
| Trp 01 | 0.44 ± 0.33 | — | — | — | |
| Gln 02 | 0.15 ± 0.29 | — | — | — | |
| Trp 04 | 1.02 ± 0.05 | 0.05 ± 0.04 | — | — | 0.86 ± 0.10 |
| Gln 06 | 1.01 ± 0.04 | — | — | — | |
| Gln 14 | 1.01 ± 0.02 | — | — | — | |
| Gln 16 | — | 0.02 ± 0.03 | — | — | |
| Gln 18 | 1.01 ± 0.02 | 0.87 ± 0.31 | — | — | |
| Gln 19 | 1.00 ± 0.00 | — | — | — | |
| Lys 21 | — | 1.02 ± 0.04 | — | 0.75 ± 0.13 | |
| Asn 22 | — | 0.98 ± 0.04 | — | — | |
| Gln 27 | 0.65 ± 0.17 | 0.06 ± 0.13 | — | — | |
| Lys 31 | 1.19 ± 0.15 | 1.46 ± 0.66 | — | — | |
| Trp 32 | 0.99 ± 0.07 | — | — | — | |
| Ser 34 | — | 0.01 ± 0.03 | — | — | |
| Trp 36 | — | 0.94 ± 0.37 | 0.81 ± 0.13 | — | |
| Trp 38 | 0.02 ± 0.05 | 0.03 ± 0.05 | 0.83 ± 0.15 | — | |