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Relative frequency of transitions and transversions induced by polδ and EMS. The mutations spectra show the frequency of transitions and transversions generated by the mutator and EMS. The data for the individual strains were combined according to the mutagen used. The color key identifying the type of mutation is provided in the inset. Complementary mutations, such as A→C and T→G, are pooled. (a) Genome-wide profile; (b) Non-synonymous substitutions only.
