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. 2012 May 22;2012:298014. doi: 10.1155/2012/298014

Table 1.

Brief introduction of “Omics” and bioinformatics.

Omics Objects Technologies and methods Advantages Disadvantages Literatures
Genomics
(transcriptomics)
DNA,
mRNA
Gene sequence,
differential display,
subtractive hybridization,
EST, SAGE, chip technology
Gene polymorphism
Susceptibility for prognosis
and treatment
Completed database
High throughput
Nonassociation to
regulation of life
activities
Nonconsistent strictly
with mRNA expression
Wu et al. [11]
Lu et al. [12]

Proteomics Amino acids,
protein
Cleaving isotope-coded affinity tag,
2D-MS, 2D-HCLP
Performer of life function Instability
Variability
Liu et al. [14]
Wu et al. [15]

Metabonomics Metabolites NMR, GC-MS, LC-MS Amplified action
Simplicity to detect
Less numbers
Similarities in
different species
Lack of beneficial
supports
Interferences by
physiological factors
Van Wietmarschen et al. [17]
Sun et al. [18]
Liu et al. [19]

Bioinformatics Data,
bioinformation
Data mining, network analysis, topological
comparison, and so on
Totally holism Exploration of
the potential of information
Focusing on function relation
Needing
of self-development
Li [49]