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. Author manuscript; available in PMC: 2012 May 31.
Published in final edited form as: Anticancer Agents Med Chem. 2011 Oct;11(8):729–738. doi: 10.2174/187152011797378689

Figure 3. Intratumoral administration of Ad.mhIL-4.TRE.mhIL-13 mediates tumor regression and long term survival in orthotopic models of GBM.

Figure 3

Nude and Rag1−/− mice were implanted in the brain with human U251 glioma cells and human primary GBM12 cells, respectively. Five days later, they were treated with either a single intratumoral injection of control vector Ad.mhIL-4.TRE.mhIL-13 or saline. Animals were fed Dox-chow to activate transgene expression.