Fig. 4.
X-ray crystallographic structure of LF in complex with R9LF-1. (a) Additional electron density in the active site grove of LF in the complex of LF and R9LF-1. (b) A model shows the interactions of the C-terminal two residues, Leu and Argo, of the inhibitor R9LF-1 (orange) with the residues of LF (yellow). The Zn atom is in green. The inhibitor and LF are shown in a sticks model where carbon atoms are in white, nitrogen atoms in blue and oxygen atoms in red. Figure was prepared by a computer program GRASP.
