Table 1.

Responses (% reduction in frequency and duration [time] SIB) of individual macaques to extended-release naltrexone

	Treatment		Posttreatment		Long-term follow-up
	Frequency	Time	Frequency	Time	Frequency	Time
1	38%a	57%a	+17%a,b	39%a	33%	46%
2	55%a	37%a	30%a	22%a	58%	43%
3	90%a	97%a	76%a	87%a	90%	97%
4	35%a	44%a	48%a	53%a	52%	55%
5	81%a	94%a	8%a	49%a	19%	61%
6	44%a	56%a	44%a	72%a	—	—
7	4%a	4%a	59%a	49%a	—	—
8	77%	89%	—	—	—	—
Reductions are relative to baseline values; macaques 1 through 6 were considered to be responders. Data from macaque 8 were excluded from statistical analysis due to clinical illness.aP < 0.025 compared with baseline value.bThis value represents an increase in the frequency of SIB.