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. 2012 May 1;13(7):496–503. doi: 10.4161/cbt.19592

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Figure 3. IL-7 enhanced cisplatin resistance in glioma cells. (A) The expression of IL-7 and IL-7R in glioma cell lines. (B) IL-7 mRNA expression was downregulated by siRNA. (C) IL-7 protein expression was downregulated by siRNA. (D) IL-7 increased the IC50 for cisplatin in U251 cells. (E) IL-7 increased the IC50 for cisplatin in SKMG-1 cells. (F) IL-7 interference decreased the IC50 for cisplatin in U251/CP2 cells. (G) IL-7 interference decreased the IC50 for cisplatin in T98G cells.