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Cytokine levels in plasma, brain homogenates and CSF. Median concentrations (expressed in pg/ml) of cytokines in mice inoculated with either NaCl or 104 CFU/mouse of S. pneumoniae and sacrificed after 30 hours, or 6 and 30 hours respectively. Comparisons of cytokine levels between groups were calculated using the Mann-Whitney U test. (*P < 0.05; **P < 0.01).
