Table 3.

Univariate Overall and Disease-Free Survival: Kaplan-Meier medians and log-rank test

		Overall Survival				Disease-Free Survival
Covariate		Median [months] (95% CI)	N	Total N	Log-rank p-value	Median [months] (95% CI)	N	Total N	Log-rank p-value
Overall		18 (14, 25)	94	94		12 (8, 19)	64	64
Age (year)	Young (≤ 65.5)	20 (16, 47)	47	94	0.087	11 (8, 19)	38	64	0.71
	Old (> 65.5)	15 (9, 24)	47			14 (7, 25)	26
Size (cm)	Small (≤ 2.0)	25 (9, 47)	20	94	0.60	21 (8, ∞)	12	64	0.17
	Large (> 2.0)	17 (13, 22)	74			11 (7, 17)	52
Gender	Female	20 (12, 34)	41	94	0.89	10 (7, 17)	32	64	0.12
	Male	18 (12, 25)	53			19 (9, 46)	32
Race	White	17 (13, 26)	66	93	0.65	14 (8, 25)	43	64	0.59
	NonWhite	22 (8, 26)	27			10 (6, 19)	21
Grade	1/2	20 (16, 26)	74	93	0.003	14 (10, 19)	52	64	0.031
	3/4	7 (6, 14)	19			6 (2, 25)	12
Lymph Nodes	0	26 (22, 48)	27	92	0.009	21 (14, ∞)	20	63	0.008
	≥ 1	15 (12, 20)	65			9 (7, 12)	43
Tumor size by	1/2	12 (6, 22)	15	93	0.45	19 (5, ∞)	9	64	0.31
TNM stage	3/4	18 (15, 26)	78			11 (8, 19)	55
Treatment	Chemo	20 (15, 26)	82	94	<.001	14 (9, 19)	62	64	0.013
	No chemo	6 (3, ∞)	12			5	2
RRM1	Low	20 (15, 25)	61	93	0.50	12 (8, 21)	40	63	0.76
IHC Interp.	High	14 (8, 48)	32			17 (5, ∞)	23
RRM1	Low	24 (16, 26)	39	49	0.21	14 (8, 21)	28	34	0.48
PCR Interp.	High	48 (3, 48)	10			17 (11, 17)	6
ERCC	Low	20 (12, 25)	41	94	0.83	14 (8, 25)	26	64	0.39
IHC Interp.	High	17 (12, 26)	53			12 (7, 19)	38
ERCC	Low	16 (12, 25)	46	79	0.39	10 (7, 19)	29	56	0.74
PCR Interp.	High	22 (9, 48)	33			14 (6, 21)	27

Abbreviations: ∞ = infinity; Interp. = Interpretation