Table 4.
Multivariate cox regression analysis for overall survival
| A. Survival in Pancreatic CA: Relative Gene Expression (N = 42) | |||
|---|---|---|---|
| Multivariate | |||
| Variable (Comparison) |
Hazard Ratio (95% CI) |
p-value† | |
| Year of Diagnosis | one year increase | 0.97 (0.69, 1.35) | 0.836 |
| Age | ≥ 65.5 vs. < 65.5 | 1.53 (0.54, 4.33) | 0.419 |
| Positive Lymph Nodes | Any vs. None | 0.80 (0.29, 2.22) | 0.672 |
| Treatment received | No Chemo vs. Chemo | 13.09 (1.71,100.2) | 0.013 |
| ERCC1 Rel Gene Expression (PCR) | Low vs. High | 0.86 (0.26, 2.81) | 0.797 |
| RRM1 Rel Gene Expression (PCR) | Low vs. High | 17.58 (1.45,213.5) | 0.024 |
| B. Survival in Pancreatic CA: Protein Expression by IHC Score (N = 91) | |||
| Multivariate | |||
| Variable (Comparison) |
Hazard Ratio (95% CI) |
p-value† | |
| Year of Diagnosis | one year increase | 0.86 (0.71, 1.02) | 0.088 |
| Age | ≥ 65.5 vs. < 65.5 | 1.36 (0.74, 2.52) | 0.320 |
| Positive Lymph Nodes | Any vs. None | 2.34 (1.21, 4.52) | 0.011 |
| Treatment | No Chemo vs. Chemo | 3.04 (1.25, 7.41) | 0.014 |
| ERCC1 IHC | Low vs. High | 0.96 (0.53, 1.74) | 0.888 |
| RRM1 IHC | Low vs. High | 0.83 (0.42, 1.63) | 0.583 |
Stratified by Grade
† Cox regression