Table 1.
Characteristics of the reconstructed metabolic models iLC915 and iSS884 of Pichia pastoris and stipitis, in comparison with the S. cerevisiae model iIN800 and iMM904
| Characteristics | P. stipitis | P. pastoris | S. cerevisiae | |||
|---|---|---|---|---|---|---|
| iSS884 | iLC915 | PpaMBEL1254 | iPP668 | iMM904 | iIN800 | |
| Reactions | 1332 | 1423 | 1202 | 1354 | 1312 | 1446 |
| Cytoplasm | 824 | 790 | 604 | 623 | 635 | 906 |
| Mitochondria | 207 | 205 | 155 | 163 | 180 | 161 |
| Peroxisome | 60 | 64 | 66 | 66 | 63 | |
| Vacuole | 12 | 6 | 3 | 3 | ||
| ER | 34 | 7 | 15 | 17 | ||
| Golgi | 4 | 8 | 4 | 2 | ||
| Nucleus | 17 | 16 | 18 | |||
| Extracellular | 11 | 12 | 7 | |||
| Transport | 239 | 314 | 328 | 452 | 387 | 379 |
| Metabolites | 920 | 899 | 1147 | 1177 | 1168 | 1013 |
| Gene coverage (%) | 15.1 | 17.2 | 9.9 | 12.6 | 13.7 | 12.11 |
| Coding genes | 5841 | 5313 | 5313 | 5313 | 6607 | 6607 |
Characteristics of the previous GEMs of P. pastoris are also included to compare with iLC915