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. 2012 May 31;8(5):e1002724. doi: 10.1371/journal.pgen.1002724

Figure 6. Atrial and ventricular connexins and sodium channel genes expression levels in wt and Ts65Dn mice.

Figure 6

(A) Atrial; (B) ventricular. Connexins and sodium channels genes expression levels were assessed by qRT-PCR using RNA extracted from adult mice cardiac atria and ventricle separately. Ts65Dn show an overall decrease in connexin and sodium channel mRNA expression except for Cx45 and Cx30.2 in the atria. Cx40 expression level is reduced in the ventricles. No amplification was obtained for Cx30.2 in ventricle extracts confirming its atria specific expression pattern. Mean±sem with Student t-test P-values, N = 7 and 5 for Ts65Dn and wt respectively.