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. 2012 May 31;8(5):e1002534. doi: 10.1371/journal.pcbi.1002534

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Stochastic simulations were used with genome length and mean base incorporation rate . The initial population () contained random sequences and a single master sequence with relative fitness . The inverse fidelity was given by Eq. (25) with and . A: Relative frequency of the master sequence (initially ). B: Average of the fractional Hamming distance (HD; initially).

Inline graphic — Stochastic simulations were used with genome length and mean base incorporation rate . The initial population () contained random sequences and a single master sequence with relative fitness . The inverse fidelity was given by Eq. (25) with and . A: Relative frequency of the master sequence (initially ). B: Average of the fractional Hamming distance (HD; initially).