Table 1. Genes induced over twofold following infection of C. elegans with hly(+) V. cholerae strains.
Gene Name | Description | CVD109/CVD110 fold change | DhlyA/E7946 fold change | Reported Immune response function |
clec-45 | C-type Lectin | 14.4 | 17.8 | Schulenburg et al, 2007 |
clec-174 | C-type Lectin | 9.9 | 10.1 | Schulenburg et al, 2007 |
C23G10.11 | hypothetical protein/Confirmed | 6.0 | 9.7 | Shapira et al, 2006 |
fmo-2 | Flavin-containing MonoOxygenase family | 2.3 | 8.9 | Irazoqui et al, 2008 |
dct-5 | DAF-16/FOXO Controlled, germline Tumor affecting | 4.7 | 7.9 | |
col-41 | Collagen | 5.7 | 6.2 | |
col-90 | Collagen | 6.5 | 5.8 | |
grd-6 | Groundhog (hedgehog-like family) | 3.6 | 5.6 | |
B0024.4 | hypothetical protein/Confirmed | 3.0 | 5.2 | |
F35B3.4 | hypothetical protein/Confirmed | 3.9 | 4.9 | |
F55G11.4 | hypothetical protein/Confirmed | 3.7 | 4.5 | Alper et al, 2007 |
Y47D7A.13 | hypothetical protein/Partially confirmed | 3.2 | 4.2 | |
col-54 | Collagen | 3.6 | 4.1 | |
C25H3.10 | hypothetical protein | 2.6 | 4.1 | |
pqn-5 | Prion-like-(Q/N-rich)-domain-bearing protein | 3.3 | 3.9 | Russell et al, 2008 |
C42D4.3 | hypothetical protein/Confirmed | 2.5 | 3.7 | |
abu-6 | Activated in Blocked Unfolded protein response | 3.2 | 3.6 | Russell et al, 2008 |
C50F7.5 | hypothetical protein/Partially confirmed | 2.8 | 3.6 | |
F53A9.2 | hypothetical protein/Confirmed | 2.3 | 3.5 | |
F49H6.13 | hypothetical protein/Partially confirmed | 3.2 | 3.4 | |
abu-8 | Activated in Blocked Unfolded protein response | 2.5 | 3.2 | Russell et al, 2008 |
toh-1 | Tollish (Tolloid and BMP-1 family) | 2.1 | 3.1 | |
abu-7 | Activated in Blocked Unfolded protein response | 2.9 | 3.1 | Russell et al, 2008 |
lips-6 | Lipase related | 5.1 | 3.1 | |
F22H10.2 | hypothetical protein/Partially confirmed | 2.2 | 3.0 | |
C35C5.8 | hypothetical protein | 2.5 | 3.0 | |
F44G3.10 | hypothetical protein/Confirmed | 2.2 | 2.9 | |
col-156 | Collagen | 3.0 | 2.8 | |
dod-24 | Downstream Of DAF-16 (regulated by DAF-16) | 3.0 | 2.8 | Troemel et al, 2006Styer et al, 2008 |
toh-1 | Tollish (Tolloid and BMP-1 family) | 2.0 | 2.8 | |
clec-209 | C-type Lectin | 3.7 | 2.8 | Schulenburg et al, 2007 |
T22F3.11 | hypothetical protein | 2.1 | 2.8 | |
glc-1 | Glutamate-gated ChLoride channel | 2.1 | 2.7 | |
ZK180.5 | hypothetical protein | 4.0 | 2.7 | |
Y54G2A.11 | hypothetical protein | 2.4 | 2.7 | |
dod-22 | Downstream Of DAF-16 (regulated by DAF-16) | 2.1 | 2.5 | Shapira et al, 2006Alper et al, 2007 |
clec-17 | C-type Lectin | 2.8 | 2.5 | O'Rourke et al, 2006Schulenburg et al, 2007 |
Y95B8A.2 | hypothetical protein/Confirmed | 2.4 | 2.5 | |
grd-14 | Groundhog (hedgehog-like family) | 3.6 | 2.4 | |
nspb-12 | Nematode Specific Peptide family, group B | 2.5 | 2.4 | |
F54B8.4 | hypothetical protein/Partially_confirmed | 2.1 | 2.4 | |
clec-47 | C-type Lectin | 2.3 | 2.4 | Schulenburg et al, 2007 |
lgc-21 | Ligand-Gated ion Channel | 3.2 | 2.4 | |
F53A9.8 | hypothetical protein/Confirmed | 2.5 | 2.3 | O'Rourke et al, 2006 |
C05E7.2 | hypothetical protein/Partially_confirmed | 2.6 | 2.3 | |
D2096.6 | hypothetical protein/Partially_confirmed | 2.7 | 2.3 | |
Y42A5A.3 | hypothetical protein/Confirmed | 2.0 | 2.3 | Troemel et al, 2006 |
C06E8.5 | bacterial permeability-increasing protein | 2.0 | 2.2 | |
C28H8.5 | hypothetical protein | 4.3 | 2.2 | |
F41E6.11 | hypothetical protein/Partially_confirmed | 2.2 | 2.1 | |
nspb-11 | Nematode Specific Peptide family, group B | 2.3 | 2.1 | |
T12D8.5 | hypothetical protein/Confirmed | 2.0 | 2.1 | |
ZK1307.2 | hypothetical protein/Confirmed | 2.3 | 2.1 | |
T22B2.6 | hypothetical protein/Confirmed | 2.5 | 2.1 | |
mup-4 | Muscle Positioning | 2.7 | 2.0 |
Only, genes induced over twofold in both CVD109/CVD110 and ΔhlyA/E7946 comparisons are listed.