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. 2012 May 31;7(5):e38200. doi: 10.1371/journal.pone.0038200

Table 1. Genes induced over twofold following infection of C. elegans with hly(+) V. cholerae strains.

Gene Name Description CVD109/CVD110 fold change DhlyA/E7946 fold change Reported Immune response function
clec-45 C-type Lectin 14.4 17.8 Schulenburg et al, 2007
clec-174 C-type Lectin 9.9 10.1 Schulenburg et al, 2007
C23G10.11 hypothetical protein/Confirmed 6.0 9.7 Shapira et al, 2006
fmo-2 Flavin-containing MonoOxygenase family 2.3 8.9 Irazoqui et al, 2008
dct-5 DAF-16/FOXO Controlled, germline Tumor affecting 4.7 7.9
col-41 Collagen 5.7 6.2
col-90 Collagen 6.5 5.8
grd-6 Groundhog (hedgehog-like family) 3.6 5.6
B0024.4 hypothetical protein/Confirmed 3.0 5.2
F35B3.4 hypothetical protein/Confirmed 3.9 4.9
F55G11.4 hypothetical protein/Confirmed 3.7 4.5 Alper et al, 2007
Y47D7A.13 hypothetical protein/Partially confirmed 3.2 4.2
col-54 Collagen 3.6 4.1
C25H3.10 hypothetical protein 2.6 4.1
pqn-5 Prion-like-(Q/N-rich)-domain-bearing protein 3.3 3.9 Russell et al, 2008
C42D4.3 hypothetical protein/Confirmed 2.5 3.7
abu-6 Activated in Blocked Unfolded protein response 3.2 3.6 Russell et al, 2008
C50F7.5 hypothetical protein/Partially confirmed 2.8 3.6
F53A9.2 hypothetical protein/Confirmed 2.3 3.5
F49H6.13 hypothetical protein/Partially confirmed 3.2 3.4
abu-8 Activated in Blocked Unfolded protein response 2.5 3.2 Russell et al, 2008
toh-1 Tollish (Tolloid and BMP-1 family) 2.1 3.1
abu-7 Activated in Blocked Unfolded protein response 2.9 3.1 Russell et al, 2008
lips-6 Lipase related 5.1 3.1
F22H10.2 hypothetical protein/Partially confirmed 2.2 3.0
C35C5.8 hypothetical protein 2.5 3.0
F44G3.10 hypothetical protein/Confirmed 2.2 2.9
col-156 Collagen 3.0 2.8
dod-24 Downstream Of DAF-16 (regulated by DAF-16) 3.0 2.8 Troemel et al, 2006Styer et al, 2008
toh-1 Tollish (Tolloid and BMP-1 family) 2.0 2.8
clec-209 C-type Lectin 3.7 2.8 Schulenburg et al, 2007
T22F3.11 hypothetical protein 2.1 2.8
glc-1 Glutamate-gated ChLoride channel 2.1 2.7
ZK180.5 hypothetical protein 4.0 2.7
Y54G2A.11 hypothetical protein 2.4 2.7
dod-22 Downstream Of DAF-16 (regulated by DAF-16) 2.1 2.5 Shapira et al, 2006Alper et al, 2007
clec-17 C-type Lectin 2.8 2.5 O'Rourke et al, 2006Schulenburg et al, 2007
Y95B8A.2 hypothetical protein/Confirmed 2.4 2.5
grd-14 Groundhog (hedgehog-like family) 3.6 2.4
nspb-12 Nematode Specific Peptide family, group B 2.5 2.4
F54B8.4 hypothetical protein/Partially_confirmed 2.1 2.4
clec-47 C-type Lectin 2.3 2.4 Schulenburg et al, 2007
lgc-21 Ligand-Gated ion Channel 3.2 2.4
F53A9.8 hypothetical protein/Confirmed 2.5 2.3 O'Rourke et al, 2006
C05E7.2 hypothetical protein/Partially_confirmed 2.6 2.3
D2096.6 hypothetical protein/Partially_confirmed 2.7 2.3
Y42A5A.3 hypothetical protein/Confirmed 2.0 2.3 Troemel et al, 2006
C06E8.5 bacterial permeability-increasing protein 2.0 2.2
C28H8.5 hypothetical protein 4.3 2.2
F41E6.11 hypothetical protein/Partially_confirmed 2.2 2.1
nspb-11 Nematode Specific Peptide family, group B 2.3 2.1
T12D8.5 hypothetical protein/Confirmed 2.0 2.1
ZK1307.2 hypothetical protein/Confirmed 2.3 2.1
T22B2.6 hypothetical protein/Confirmed 2.5 2.1
mup-4 Muscle Positioning 2.7 2.0

Only, genes induced over twofold in both CVD109/CVD110 and ΔhlyA/E7946 comparisons are listed.