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. 2012 May 31;7(5):e38442. doi: 10.1371/journal.pone.0038442

Table 2. The anesthetic doses used during selected procedures.

Study Group mass induction dose ketamine diazepam
kg mg mg/kg mg mg/kg mg µg/kg
sedated weanling 106 (22) 58.0 (11.0) 0.55 (0.10) 630 (73) 5.94 (0.69) 4.6 (3.9) 4.36 (3.72)
sedated yearling 111 (11) 64.3 (11.0) 0.58 (0.10) 594 (110) 5.35 (0.99) 12.0 (2.9) 10.81 (2.59)
early weaning 114 (17) 50.0 (0.0) 0.44 (0.00) 674 (194) 5.91 (1.70) 2.0 (2.3) 1.75 (1.99)
late weaning 94 (14) 45.0 (6.8) 0.48 (0.07) 372 (100) 3.96 (1.06) 0.3 (0.7) 0.32 (0.71)
early lactation 536 (33) 219.0 (22.5) 0.41 (0.04) 2200 (262) 4.10 (0.49) 42.5 (24.1) 7.93 (4.50)
late lactation 374 (50) 180.0 (12.6) 0.48 (0.03) 2286 (507) 6.11 (1.36) 14.3 (10.6) 3.82 (2.83)
molting female 311 (21) 168.3 (32.0) 0.54 (0.10) 1675 (301) 5.39 (0.97) 10.2 (7.1) 3.28 (2.28)
Grand Mean 0.496 (0.062) 5.25 (0.88) 4.61 (3.62)

The total drug doses are reported as the mean and (sd). The induction dose was equal parts tiletamine and zolazepam—values shown are for each. For each agent the total dose, in mg or µg, and mass-specific doses are reported. The induction dose was administered in a single intramuscular injection; ketamine and diazepam were administered intravenously periodically over 3–3.5 hours of sedation. Data of anesthetic doses for adult males are not reported.