Table 1. Various fragments of CaIX-P1 were tested on CA IX positive human renal cell carcinoma SKRC 52 cells.
Peptide | Sequence | Ratio binding-derivative to binding-CaIX-P1 (10 min) |
CaIX-P1 | YNTNHVPLSPKY | 1 |
CaIX-P1-3-6 | TNHVy | 0.29 |
CaIX-P1-3-7 | TNHVPy | 0.60 |
CaIX-P1-3-8 | TNHVPLy | 0.76 |
CaIX-P1-3-9 | TNHVPLSy | 1.57 |
CaIX-P1-3-10 | TNHVPLSPy | 5.40 |
CaIX-P1-4-7 | NHVPy | 0.79 |
CaIX-P1-4-8 | NHVPLy | 0.82 |
CaIX-P1-4-9 | NHVPLSy | 2.62 |
CaIX-P1-4-10 | NHVPLSPy | 5.84 |
CaIX-P1-5-9 | HVPLSy | 0.06 |
CaIX-P1-5-12 | HVPLSPKy | 0.10 |
CaIX-P1-6-10 | VPLSPy | 0.25 |
CaIX-P1-8-10 | LSPy | 0.04 |
Ratio binding-fragment to binding-CaIX-P1.