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. 2012 May 31;7(5):e37304. doi: 10.1371/journal.pone.0037304

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Hagemann et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Transcripts for the ferritin heavy chain gene Fth1 are elevated in both olfactory bulb and hippocampus from Gfap^+/R236H mice, and are reduced to wild-type levels with loss of Nrf2. (B) Fth1 protein levels, however remain unchanged in all genotypes. (8 wks of age, n = 4, t-test **p>0.01, ***p > 0.001 comparing Gfap^+/R236H/Nrf2^+/+ with Gfap^+/R236H/Nrf2^−/−).