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. 2012 May 31;7(5):e37928. doi: 10.1371/journal.pone.0037928

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Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The percentage of DNA methylation levels at promoter CpG islands were analyzed in bisulfite-modified genomic DNA extracted from matched pairs of non-cancerous (normal) and breast tumors (tumor) tissue samples obtained from AA and AE cancer patients. Y axis, percentage of methylated cytosines in the samples as obtained from pyrosequencing. X axis, normal and tumor tissues obtained from AA and EA. P value is indicated for each gene (Mann-Whitney). Adj. P: adjusted P value (Bonferroni).