Figure 3. Association of haplotypes in candidate genes with drug responses.
Only association of major haplotypes in pfmdr1 and pfmdr6 with in vitro responses to artesunate (AS), dihydroartemisinin (DHA), mefloquine (MQ) and lumefantrine (LMF) are plotted. IC50 values are shown as mean + standard deviation. * indicates significant difference (P<0.05) in sensitivity between the haplotypes after Bonferroni correction. # indicates that this pfmdr6 haplotype was significantly more sensitive to LMF than 3D7.