Table 1. Frequencies of genotypes of GST polymorphisms in ARC patients and controls.
| Genotype | Sex | Patients with ARC | Controls | PC | OR (95% CI) |
|---|---|---|---|---|---|
|
GSTM1 |
Both sex |
||||
| Positive |
|
246 (58.3%) |
139 (44.6%) |
0.0002 |
1.74 (1.30–2.34) |
| Null |
|
176 (41.7%) |
173 (55.4%) |
||
|
GSTT1 | |||||
| Positive |
|
201 (47.6%) |
174 (55.8%) |
0.186 |
1.22 (0.91–1.63) |
| Null |
|
221 (52.4%) |
138 (44.2%) |
||
|
GSTM1 |
Male |
||||
| Positive |
|
122 (62.8%) |
68 (46.3%) |
0.002 |
1.97 (1.27–3.04) |
| Null |
|
72 (37.2%) |
79 (53.7%) |
||
|
GSTT1 | |||||
| Positive |
|
95 (48.9%) |
83 (56.4%) |
0.170 |
0.74 (0.48–1.14) |
| Null |
|
99 (51.1%) |
64 (43.6%) |
||
|
GSTM1 |
Female |
||||
| Positive |
|
124 (54.4%) |
71 (43.1%) |
0.026 |
1.58 (1.05–2.36) |
| Null |
|
104 (45.6%) |
94 (56.9%) |
||
|
GSTT1 | |||||
| Positive |
|
106 (46.5%) |
91 (55.1%) |
0.090 | 0.71 (0.47–1.06) |
| Null | 122 (53.5%) | 74 (44.9%) | |||
GST, glutathione S-transferase; OR, odds ratio; Pc, Bonferroni corrected p value.