Fig. 4.
In vivo efficacy of salinomycin in mice. (A) P. berghei parasite load in mouse livers 44 h after infection with luciferase-expressing sporozoites, determined by luminescence in vehicle-treated (black) and salinomycin-treated (blue) animals. (B) Plots of blood parasitemia at days 2–4 after infection for vehicle-treated (black) and salinomycin-treated (blue) animals. Mice received a single treatment by oral administration of 30 mg/kgb.w. salinomycin or an equivalent amount of vehicle (controls).