Table 1. Demographic and clinical variables of schizophrenia patients and healthy controls.
| Patients | Controls | t-test (P) | |
|---|---|---|---|
| Gender (male/female) | 10/10 | 10/10 | |
| Age (year) | 47.9±13.4 | 47.6±14.6 | 0.937 |
| Body weight (kg) | 63.2±12.0 | 61.5±9.8 | 0.625 |
| Body mass index (kg/m2) | 24.1±4.0 | 23.0±2.6 | 0.311 |
| Age of onset (year) | 28.9±10.8 | ||
| Duration of illness (year) | 19.1±13.3 | ||
| Number of inpatients (%) | 17 (85.0) | ||
| Psychopathology score (PANSS) | |||
| Total | 61.4±13.3 | ||
| Positive scale | 11.3±3.7 | ||
| Negative scale | 19.0±7.3 | ||
| General psychopathology scale | 31.1±7.0 | ||
| CPZeq (mg per day) | 844.0±639.6 | ||
| AST (U l–1, reference value:10–40) | 19.1±6.1 | 18.7±4.5 | 0.792 |
| ALT (U l–1, reference value:5–40) | 18.9±10.5 | 12.4±6.0 | 0.023 |
| Cholinesterase (U l–1, reference value: m 242–495; f 200–459) | 300.9±90.3 | 327.7±57.3 | 0.269 |
| BUN (mg dl–1, reference value: 8.0–22.0) | 10.0±2.9 | 12.6±3.7 | 0.018 |
| Cr (mg dl–1, reference value: m, 0.61–1.04; f, 0.47–0.79) | 0.68±0.15 | 0.68±0.13 | 0.938 |
| Total protein (g dl–1, reference value: 6.7–8.3) | 7.0±0.5 | ||
| Albumin (g dl–1, reference value: 3.8–5.3) | 4.3±0.5 | ||
| Total bilirubin (mg dl–1, reference value: 0.2–1.2) | 0.5±0.2 | ||
| Platelet counts ( × 104 per μl, reference value: 14–35) | 22.1±5.5 |
Abbreviations: BUN, blood urea nitrogen; CPZeq, total antipsychotic dose in chlorpromazine equivalents; Cr, creatinine; f, female; m, male; PANSS, positive and negative symptom scale.
One patient was missing the total protein, albumin, total bilirubin and platelet counts data.