. 2011 May 1;2(2):85–96. doi: 10.1007/s13148-011-0037-3

Table 1.

CpGs, histone modifications, and other factors or miRNAs that affect the expression of epigenetically regulated mucin genes

Mucins	Promoter methylation sites	Histone modification	Factors or miRNA
MUC1	−70 to +20	H3-me2K9, aceK9	miR-125b, miRNA-145, miR-1226
MUC2	−3,269, −3,199, −2,331, −1,912, −338 to +158	H3-me2K4, me3K4, meK9, me2K9, aceK9, me2K27, aceK27, H3-ace, H4-ace	DNMT1, HDAC2
MUC3A	−345 to −75	N.D.	N.D.
MUC4	−121 to −81^a	H3-ace, me2K9, aceK9, me3K27	Sp1, DNMT3A, DNMT3B, HDAC1, HDAC3
MUC4	−170 to −102^b	H3-ace, me2K9, aceK9, me3K27	Sp1, DNMT3A, DNMT3B, HDAC1, HDAC3
MUC5AC	−3,718 to −3,670	H3-me2K9, aceK9	N.D.
MUC5B	−2,677/−2,163	H3-me2K4, me3K4, meK9	DNMT1, HDAC2
MUC5B	−434/−421	me2K9, aceK9, me2K27, aceK27	DNMT1, HDAC2
MUC17	−179 to +52	H3-me2K9, aceK9	N.D.

ND not determined

^aRegion reported by Vincent et al.

^bRegion reported by Yamada et al.