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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Mar;15(3):360–366. doi: 10.1016/j.bbmt.2008.12.495

Table 2.

Multivariate analysis for relapse in children who were diagnosed with AML (N=156) and received unrelated donor BMT.

Variables N Odds Ratio
(95% Confidence Interval )
P-value
HLA matching
 (1) Matched 69 1.00 a
 (2) 7/8 matched 87 0.63 (0.26, 1.55) 0.36
Other significant
covariates:
Grade III-IV aGVHD
 (1) No 89 1.00 a
 (2) Yes 67 0.58 (0.22, 1.58) 0.26
Disease stage < 0.0001
 (1) Early 33 1.00 a
 (2) Intermediate 69 0.90 (0.23, 3.54) 0.88
 (3) Advanced 54 12.59 (3.09, 51.32) 0.0004
Recipient age categories 0.0059
 (1) < 5 years 46 1.00 a
 (2) 6-10 years 32 0.40 (0.13, 1.28) 0.12
 (3) 11-15 years 47 0.12 (0.04, 0.39) 0.0005
 (4) 16-17.9 years 31 0.12 (0.02, 0.65) 0.014
Transplant year group
 1999 - 2003 64 1.00 a
 1990 - 1998 92 0.14 (0.13, 0.73) 0.0075
a

Reference group.

Acute GVHD III-IV is treated as a time-dependent variable.