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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Eur J Med Chem. 2012 Jan 15;49:200–210. doi: 10.1016/j.ejmech.2012.01.012

Fig. 7.

Fig. 7

The docking of a) 6-nitroquipazine and b) quipazine to SERT model in closed conformation to the putative binding site. The aminoacids Tyr176 and Phe355 form an aromatic lid that prevents from binding of long arylopiperazine analogues to SERT in closed conformation.