Table 2. Principal component analysis of the mean intensity and frequency of symptoms in the Reflux Disease Questionnaire electronic Diary during the 7 days prior to randomization (all enrolled eligible patients, N=580).

RESQ-eD item	Intensity			Frequency
	Factor 1	Factor 2	Factor 3	Factor 1	Factor 2	Factor 3
Burning feeling, breastbone	86	27	24	13	89	11
Pain, breastbone	83	25	27	19	77	18
Heartburn	82	35	18	16	84	0
Acid taste in mouth	34	80	31	79	24	26
Bitter taste in mouth	33	79	34	79	21	27
Unpleasant movement of material	35	82	29	88	19	19
Stomach contents, liquid or food	33	82	30	86	17	16
Burning feeling, upper stomach	77	39	24	35	71	18
Pain, upper stomach	75	40	27	43	62	26
Hoarseness	23	30	85	21	18	86
Cough	23	27	83	15	9	84
Difficulty swallowing	32	34	76	34	15	74
Burping	44	60	24	52	25	12

RESQ-eD, Reflux Disease Questionnaire electronic Diary.