TABLE 1.

STDD enhancements (%) for compounds 1–5 binding to antibody C3.1 at a 15:1 compound:binding site ratio

Enhancements are normalized to the strongest signal in each spectrum.

Resonance	STD Enhancement
	1	2	3	4	5
	%
Isolated resonances
H1A	73	87	64	100	41
H2A	86	76	96	100	64
H3A		100
H4A		60		86	30
H4′A					16
H6A					18
H6′A				60
H1B	55	47	82	60	88
H2B	64	44	90	63	88
H4B				67
H6′B				92
H1C		31	43	38	58
H2C		49	36	60	54
H3C				55
H4C				20
H4′C				24
H1D			40
H2D			58
Pr 1-CH		53	61
Pr 2-CH2		29	50
Pr 3-CH3		24	50
OCH3	50			67	78
Overlapping resonances
H5AB	82			100
H5BC					100
H5ABC		64
H5ABCD			78
H3B,4B,4C					90
H3A,6B,6C					78
H5A,6′A,3C					50
H6AB	66			100
H6ABC		56
H6ABCD			60
H6′AB	73
H6′ABC		53
H6′ABCD			62
H3AB	77		100
H4AB	100		87
H6C,6′C,3B,5C				65
H3B,3C,4B,4C, Pr 1-CH'		58
H3C,3D,4C,4D, Pr 1-CH'			55