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LSF inhibition causes slower cell cycle progression through S-phase. Control-1 and LSFdn-15 clones of QGY-7703 cells were synchronized by double thymidine block and then allowed to enter the cell cycle by thymidine removal. Samples were collected every two hours and cell cycle was analyzed by flow cytometry of propidium iodide-stained DNA. A. Histograms of the cell cycle profile. B. Graphical representation of the percentage of cells in eachphase of the cell cycle.
