Table 1.
A list of gene expression levels in a benign tumor and a malignant melanoma developed in a RET-mouse.
| Gene | Melanocytic tumors in a RET-mouse | ||
|---|---|---|---|
| Expression values in Benign | Expression values in Malignant | Benign/Malignant Ratio | |
| CyclinD1 | 911.5 | 30871.8 | 33.869 |
| Melanoma cell adhesion molecule(MCAM) | 441.6 | 6263.8 | 14.184 |
| Matrix metalloproteinase 2(MMP-2) | 394.3 | 4261.2 | 10.807 |
| B-cell leukemia/lymphoma 2(Bcl2) | 710.4 | 1801.1 | 2.535 |
| Transformation related protein 53(p53) | 523.9 | 209.8 | 0.400 |
| Phosphatase and tensin homolog(PTEN) | 1424.5 | 292.8 | 0.206 |
| MAD homolog 7(Smad7) | 323.9 | 40.1 | 0.124 |
| G protein gamma 2 subunit(Gng2) | 364.7 | 33.3 | 0.091 |
| G protein gamma 3 subunit(Gng3) | 133.5 | 194.9 | 1.460 |
| G protein gamma 4 subunit(Gng4) | 56.4 | 271.5 | 4.814 |
| G protein gamma 5 subunit(Gng5) | 12429.9 | 15896.5 | 1.279 |
| G protein gamma 7 subunit(Gng7) | 710.9 | 666.6 | 0.938 |
| G protein gamma 8 subunit(Gng8) | 98.5 | 216.9 | 2.202 |
| G protein gamma 10 subunit(Gng10) | 1399.2 | 736.3 | 0.526 |
| G protein gamma 11 subunit(Gng11) | 2258.5 | 10041.7 | 4.446 |
Six melanoma-related genes and nine G protein gamma subunit family genes are shown as a result of DNA microarray analysis.