Table 1.

Low-dose definitions and cutoff doses: BPA and DEHP as examples

Chemical	Estimated range of human exposures	Doses below the NOAEL	Doses below the LOAEL	Administered doses (to animals) that produce blood levels in typical humans
BPA	0.4–5 μg/kg · d (679)	No NOAEL was ever established in toxicological studies (38)	<50 mg/kg · d (38)	∼400 μg/kg · d to rodents and nonhuman primates (4, 253)
DEHP	0.5–25 μg/kg · d (680)	<5.8 mg/kg · d (681, 682)	<29 mg/kg · d (681, 682)	Unknown

Estimates of human exposure are made from consumer product consumption data but do not take into account that there are unknown sources of these chemicals. DEHP, Bis(2-ethylhexyl) phthalate.