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. 2012 Jun 1;7(6):e38381. doi: 10.1371/journal.pone.0038381

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Yin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The protein expression of Bcl-2 was reduced in the SCI group at 1 day and 3 days compared to the sham and sham/TIIA groups, whereas Bcl-2 was up-regulated in the SCI/TIIA group (A). The analyzed data are shown. (B) The cleaved caspase-3 expression began to increase at 1 day, peaked at 3 days and quickly reduced to a lower level at 7 days after SCI. However, TIIA treatment decreased the cleaved caspase-3 (C). The analyzed data are shown (D). Bars represent means ± SEM. *p<0.05 vs. sham group, ^# p<0.05 vs. SCI group.