Table 2.
Parameter | Group | Time Period | Dose of Hcrt-1 (μg) | ||
---|---|---|---|---|---|
0 | 10 | 30 | |||
Number of W bouts | |||||
Young | Hrs 1–6 | 92.25±4.39 | 73.40±5.13+ | 77.64±4.84+ | |
Hrs 7–12 | 138.25±10.23▴ | 132.25±11.93▴ | 122±3.24▴ | ||
Old | Hrs 1–6 | 118.56±7.57 | 110.51±5.03 | 110.6±5.08 | |
Hrs 7–12 | 138.8±6.50▴ | 126.9±4.23▴ | 131.1±5.29▴ | ||
Number of NR bouts | |||||
Young | Hrs 1–6 | 92.5±4.6 | 73.2±4.3+ | 77.4±4.8+ | |
Hrs 7–12 | 139.0±10.5▴ | 132.8±11.7▴ | 123.0±3.2▴ | ||
Old | Hrs 1–6 | 118.6±7.5 | 110.3±5.0 | 110.5±5.0 | |
Hrs 7–12 | 139.6±6.1▴ | 127.7±4.1▴ | 131.4±5.0▴ | ||
Number of REM bouts | |||||
Young | Hrs 1–6 | 14.5±2.3+ | 2.0±1.4*+ | 2.3±1.7*+ | |
Hrs 7–12 | 21.0±4.6+ | 28.0±2.1*+▴ | 20.8±2.9+▴ | ||
Old | Hrs 1–6 | 24.7±1.8 | 21.1±3.9 | 18.6±4.1 | |
Hrs 7–12 | 33.4±1.3▴ | 36.8±2.2▴ | 37.5±3.7 |
p<0.05 relative to vehicle;
p<0.05 between age groups;
p<0.05 early vs. late light or dark period within age group.