Table 4.
Parameter | Group | Time Period | Dose of Hcrt-2 (μg) | ||
---|---|---|---|---|---|
0 | 10 | 30 | |||
Number of W bouts | |||||
Young | Hrs 1–6 | 120.49±8.60 | 95.68±8.58 | 140.55±15.36 | |
Hrs 7–12 | 178.0 ±12.20▴ | 148.0±8.83▴ | 173.33±9.45▴ | ||
Old | Hrs 1–6 | 120.50±10.60 | 110.87±3.68 | 119.67±6.19 | |
Hrs 7–12 | 156.36±4.91▴ | 154.78±9.79▴ | 141.75±6.28▴ | ||
Number of NR bouts | |||||
Young | Hrs 1–6 | 120.74±8.60 | 93.66±8.56 | 140.21±15.36 | |
Hrs 7–12 | 179.0±12.35▴ | 148.25±8.62▴ | 173.67±9.93▴ | ||
Old | Hrs 1–6 | 119.24±10.47 | 110.37±3.5 | 118.64±6.11 | |
Hrs 7–12 | 153.0±4.33▴ | 153.9±10.03▴ | 140.75±6.10▴ | ||
Number of REM bouts | |||||
Young | Hrs 1–6 | 17.28±3.83 | 12.76±0.70 | 3.02±0.50*+ | |
Hrs 7–12 | 18.75±1.89 | 25.0±4.02▴ | 24.67±2.75▴ | ||
Old | Hrs 1–6 | 16.72±2.61 | 17.03±2.25 | 14.85±2.83 | |
Hrs 7–12 | 27.50±2.07▴ | 27.18±3.11▴ | 28.25±3.91▴ |
p<0.05 relative to vehicle;
p<0.05 between age groups;
p<0.05 early vs. late light or dark period within age group.