FIGURE 1.

Genome-wide screen for mutants with altered rates of cell death. Individual mutants from the yeast gene knock-out collection were cultured in the presence of tunicamycin (+TM) and tunicamycin plus FK506 (+TM+FK506), stained with PI, analyzed by flow cytometry, and plotted as a single point in the chart. Each point represents the percentage of dead cells in the culture containing tunicamycin versus that in the culture containing tunicamycin plus FK506. Selected mutants have been highlighted with large symbols.